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A comparative account of protein-protein interaction resources, feature-validations and application-based categorizations

IntAct

Tool nameIntAct
URLhttp://www.ebi.ac.uk/intact
Important featuresA database that provides protein-protein interactions of experimental importance. Protein-protein interactions for few specific diseases are available. Protein interactions specific to a biological process (e.g., apoptosis, cell cycle) can also be obtained. Provides interactions along with their functional associations. Interactions can be restricted to a given experimental evidence. Provides interactions related to cancer. Provides protein-drug interactions. User interaface parameters can be implied to the input.
CitationsHermjakob H, Montecchi-Palazzi L, Lewington C, Mudali S, Kerrien S, Orchard S, Vingron M, Roechert B, Roepstorff P, Valencia A, Margalit H, Armstrong J, Bairoch A, Cesareni G, Sherman D, Apweiler R. IntAct: an open source molecular interaction database. Nucleic Acids Res. 2004 Jan 1;32(Database issue):D452-5. PubMed PMID: 14681455; PubMed Central PMCID: PMC308786.
Year of publication2004
Rank by usage frequency90
Comments
FunctionPPIs for a specific disease, PPIs specific to a biological process (e.g., apoptosis), PPIs for a given article (PMID), PPIs with their functional associations, PPIs along with supporting evidences, PPIs and their categories based on evidence type, PPIs related to cancer, Viral-host PPIs
Categoryhttp://www.ebi.ac.uk/intact, A database that provides protein-protein interactions of experimental importance. Protein-protein interactions for few specific diseases are available. Protein interactions specific to a biological process (e.g., apoptosis, cell cycle) can also be obtained. Provides interactions along with their functional associations. Interactions can be restricted to a given experimental evidence. Provides interactions related to cancer. Provides protein-drug interactions. User interaface parameters can be implied to the input., Hermjakob H, Montecchi-Palazzi L, Lewington C, Mudali S, Kerrien S, Orchard S, Vingron M, Roechert B, Roepstorff P, Valencia A, Margalit H, Armstrong J, Bairoch A, Cesareni G, Sherman D, Apweiler R. IntAct: an open source molecular interaction database. Nucleic Acids Res. 2004 Jan 1;32(Database issue):D452-5. PubMed PMID: 14681455; PubMed Central PMCID: PMC308786., 2004, 90
Online/downloadable
OnlineOnline
Downloadable
Registration required
FreeFree
Paid
Working statusFunctional
FunctionPPIs and their categories based on evidence type
Category
Tool_frequency

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