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A comparative account of microRNA resources, feature-validations and application-based categorizations

miRTrail

Tool namemiRTrail
URLhttp://mirtrail.bioinf.uni-sb.de
Important featuresmiRTrail is stated to contain information on 20.000 genes, around 1.000 miRNAs, and approximately 280.000 putative interactions and can be applied to analyze microarray based expression profiles and NGS-based transcriptomic data.
CitationsLaczny C, Leidinger P, Haas J, Ludwig N, Backes C, Gerasch A, Kaufmann M, Vogel B, Katus HA, Meder B, Stahler C, Meese E, Lenhof HP, Keller A. miRTrail - a comprehensive webserver for analyzing gene and miRNA patterns to enhance the understanding of regulatory mechanisms in diseases. BMC Bioinformatics. 2012 Feb 22;13(1):36. [Epub ahead of print] PubMed PMID: 22356618.
Year of publication2012
Rank by usage frequency100
Comments
FunctionFUNCTIONAL ANALYSIS: regulation/ expression, EXPERIMENTAL data analysis, http://mirtrail.bioinf.uni-sb.de, miRTrail is stated to contain information on 20.000 genes- around 1.000 miRNAs- and approximately 280.000 putative interactions and can be applied to analyze microarray based expression profiles and NGS-based transcriptomic data., Laczny C- Leidinger P- Haas J- Ludwig N- Backes C- Gerasch A- Kaufmann M- Vogel B- Katus HA- Meder B- Stahler C- Meese E- Lenhof HP- Keller A. miRTrail - a comprehensive webserver for analyzing gene and miRNA patterns to enhance the understanding of regulatory mechanisms in diseases. BMC Bioinformatics. 2012 Feb 22;13(1):36. [Epub ahead of print] PubMed PMID: 22356618., 2012, 100, Online, I. SPECIES SUPPORTED INCLUDE: human- mouse- zebrafish II. QUERY OR INPUT DATA: 1. Upload microRNA and mRNA files( use gene symbols and miRBase as identifiers for the mRNAs and microRNAs- respectively). For each set- enter a tab-separated- plain text file containing one ID per line- a tab-stop- and either 1 for up-regulated or -1 for down-regulated. 2. Enter disease of interest (optional) 3. Enter target prediction threshold (0.01) III. OUTPUT DATA: tabular format and diagrammatic representation of results depicting target mRNAs and deregulated mRNAs- significant KEGG categories- common categories and network analysis.
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