miRTrail Tool name | miRTrail |
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URL | http://mirtrail.bioinf.uni-sb.de |
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Important features | miRTrail is stated to contain information on 20.000 genes, around 1.000 miRNAs, and approximately 280.000 putative interactions and can be applied to analyze microarray based expression profiles and NGS-based transcriptomic data. |
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Citations | Laczny C, Leidinger P, Haas J, Ludwig N, Backes C, Gerasch A, Kaufmann M, Vogel B, Katus HA, Meder B, Stahler C, Meese E, Lenhof HP, Keller A. miRTrail - a comprehensive webserver for analyzing gene and miRNA patterns to enhance the understanding of regulatory mechanisms in diseases. BMC Bioinformatics. 2012 Feb 22;13(1):36. [Epub ahead of print] PubMed PMID: 22356618. |
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Year of publication | 2012 |
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Rank by usage frequency | 100 |
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Comments | |
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Function | FUNCTIONAL ANALYSIS: regulation/ expression, EXPERIMENTAL data analysis, http://mirtrail.bioinf.uni-sb.de, miRTrail is stated to contain information on 20.000 genes- around 1.000 miRNAs- and approximately 280.000 putative interactions and can be applied to analyze microarray based expression profiles and NGS-based transcriptomic data., Laczny C- Leidinger P- Haas J- Ludwig N- Backes C- Gerasch A- Kaufmann M- Vogel B- Katus HA- Meder B- Stahler C- Meese E- Lenhof HP- Keller A. miRTrail - a comprehensive webserver for analyzing gene and miRNA patterns to enhance the understanding of regulatory mechanisms in diseases. BMC Bioinformatics. 2012 Feb 22;13(1):36. [Epub ahead of print] PubMed PMID: 22356618., 2012, 100, Online, I. SPECIES SUPPORTED INCLUDE: human- mouse- zebrafish II. QUERY OR INPUT DATA: 1. Upload microRNA and mRNA files( use gene symbols and miRBase as identifiers for the mRNAs and microRNAs- respectively). For each set- enter a tab-separated- plain text file containing one ID per line- a tab-stop- and either 1 for up-regulated or -1 for down-regulated. 2. Enter disease of interest (optional) 3. Enter target prediction threshold (0.01) III. OUTPUT DATA: tabular format and diagrammatic representation of results depicting target mRNAs and deregulated mRNAs- significant KEGG categories- common categories and network analysis. |
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