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A comparative account of microRNA resources, feature-validations and application-based categorizations

TargetRank

Tool nameTargetRank
URLhttp://genes.mit.edu/targetrank/
Important featuresComputational tool to identify microRNA target sites based on several parameters such as seed match (many types), AU content, presence of A or U at position t9 etc.
CitationsNielsen CB, Shomron N, Sandberg R, Hornstein E, Kitzman J, Burge CB. Determinants of targeting by endogenous and exogenous microRNAs and siRNAs. RNA. 2007 Nov;13(11):1894-910. Epub 2007 Sep 13. PubMed PMID: 17872505; PubMed Central PMCID: PMC2040081.
Year of publication2007
Rank by usage frequency100
CommentsDataset downloadable
FunctionEXPERIMENTAL data analysis, SPECIES: human, SPECIES: mouse, http://genes.mit.edu/targetrank/, Computational tool to identify microRNA target sites based on several parameters such as seed match (many types)- AU content- presence of A or U at position t9 etc., Nielsen CB- Shomron N- Sandberg R- Hornstein E- Kitzman J- Burge CB. Determinants of targeting by endogenous and exogenous microRNAs and siRNAs. RNA. 2007 Nov;13(11):1894-910. Epub 2007 Sep 13. PubMed PMID: 17872505; PubMed Central PMCID: PMC2040081. , 2007, 100, Dataset downloadable, Online, I. SPECIES SUPPORTED INCLUDE: human. mouse 2.II. QUERY OR INPUT DATA: Select a species- enter an siRNA or miRNA sequence (5'- 3' orientation- only first 8 nt required or input human or mouse miRBase microRNA gene name) III. OUTPUT DATA: details on predicted microRNA targets (top 100 displayed) IV. ADDITIONAL INFORMATION: Target sites for siRNA or experimental studies can be determined by this method.(human- mouse)
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