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A comparative account of microRNA resources, feature-validations and application-based categorizations

PhenoMir

Tool namePhenoMir
URLhttp://mips.helmholtz-muenchen.de/phenomir
Important featuresWeb based resource on altered microRNA function in disease and physiological processes.
CitationsRuepp A, Kowarsch A, Schmidl D, Buggenthin F, Brauner B, Dunger I, Fobo G, Frishman G, Montrone C, Theis FJ. PhenomiR: a knowledgebase for microRNA expression in diseases and biological processes. Genome Biol. 2010 Jan 20;11(1):R6. PubMed PMID: 20089154
Year of publication2010
Rank by usage frequency100
Comments
FunctionDISEASE/ TISSUE SPECIFIC, http://mips.helmholtz-muenchen.de/phenomir, Web based resource on altered microRNA function in disease and physiological processes. , Ruepp A- Kowarsch A- Schmidl D- Buggenthin F- Brauner B- Dunger I- Fobo G- Frishman G- Montrone C- Theis FJ. PhenomiR: a knowledgebase for microRNA expression in diseases and biological processes. Genome Biol. 2010 Jan 20;11(1):R6. PubMed PMID: 20089154 , 2010, 100, Online/ downloadable , I. QUERY OR INPUT DATA: 1. General search- entries- miRNAs 2. Specific search: Database- database id- disease class- mirna name/ accession id- pubmed id- tissue/ cell line- bioprocess- study design- sample info- organism name- method- evidence- target gene- disease comment- tissue comment- general comment- mirna comment- list as entries- miRNAs 3. List all entries 4. List all diseases 5. List all microRNA II. OUTPUT DATA: details on microRNAs and their state of expression in disease states or biological processes. III. ADDITIONAL INFORMATION: According to the authors- out of 542 PhenomiR entries- 90 provide information about microRNA expression in normal biological processes- such as- cardiac muscle development or eye development- which are unavailable in other sources. The differentiating feature from similar resources like miR2Disease and HMDD is that PhenomiR provides detailed experimental data such as fold-change of microRNA dysregulation etc.
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